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KCNK3 Antikörper (AA 251-411) (PerCP)

KCNK3 Reaktivität: Ratte WB, IHC, ICC, IF Wirt: Maus Monoclonal S374-48 PerCP
Produktnummer ABIN1741500
  • Target Alle KCNK3 Antikörper anzeigen
    KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
    Bindungsspezifität
    • 15
    • 15
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 251-411
    Reaktivität
    • 49
    • 29
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 52
    • 12
    Maus
    Klonalität
    • 52
    • 12
    Monoklonal
    Konjugat
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNK3 Antikörper ist konjugiert mit PerCP
    Applikation
    • 53
    • 26
    • 26
    • 16
    • 15
    • 13
    • 12
    • 6
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~50 kDa. Does not cross-react with TASK3.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical). Human: 76% identity (163/161 amino acids identical). <30% identity with TASK3.
    Klon
    S374-48
    Isotyp
    IgG2b
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    Discover our top product KCNK3 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN1741500 was sufficient for detection of TASK1 Potassium Channel in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
    Andere Bezeichnung
    KCNK3 (KCNK3 Produkte)
    Synonyme
    si:dkey-164m15.1 antikoerper, K2p3.1 antikoerper, OAT1 antikoerper, PPH4 antikoerper, TASK antikoerper, TASK-1 antikoerper, TBAK1 antikoerper, cTBAK-1 antikoerper, Task-1 antikoerper, rTASK antikoerper, KCNK3 antikoerper, potassium channel, subfamily K, member 3a antikoerper, potassium two pore domain channel subfamily K member 3 antikoerper, potassium channel, subfamily K, member 3 antikoerper, kcnk3a antikoerper, KCNK3 antikoerper, Kcnk3 antikoerper
    Hintergrund
    K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54 % identity with TASK-1, but less than 30 % identity with TASK-2 and other tandem pore K+ channels.
    Gen-ID
    29553
    NCBI Accession
    NP_203694
    UniProt
    O54912
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