PRKAG1 Antikörper (AA 230-331)

Produktnummer ABIN1724932

Produktdetails anti-PRKAG1 Antikörper

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Bindungsspezifität: AA 230-331

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRKAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PRKAG1 (AA: 230-331) expressed in E. coli.

Klon: 7H3E9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-PRKAG1 Antikörper (ABIN1724932)

Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

Details zu PRKAG1

Target: PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Andere Bezeichnung: PRKAG1 (PRKAG1 Produkte)

Synonyme: MGC68503 antikoerper, zgc:63896 antikoerper, wu:fa94d09 antikoerper, wu:fd12h04 antikoerper, AMPKG antikoerper, Prkaac antikoerper, Prkga1 antikoerper, AA571379 antikoerper, BB036179 antikoerper, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 1 antikoerper, prkag1.S antikoerper, prkag1 antikoerper, PRKAG1 antikoerper, Prkag1 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. ,

Aliases: AMPKG

Molekulargewicht: 37.6 kDa

Gen-ID: 5571

HGNC: 5571

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effekt