DARPP32 Antikörper (AA 95-204)

Produktnummer ABIN1724929

Produktdetails anti-DARPP32 Antikörper

Target: DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))

Bindungsspezifität: AA 95-204

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DARPP32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. coli.

Klon: 2G6D9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-DARPP32 Antikörper (ABIN1724929)

Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: "Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).

Hamel, Bouchard, Ferrario, Hassan, Aguilar-Mahecha, Buchanan, Quenneville, Miller, Basik: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." in: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, (2010) (PubMed).

Details zu DARPP32

Target: DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))

Andere Bezeichnung: PPP1R1B (PPP1R1B Produkte)

Synonyme: darpp32 antikoerper, darpp-32 antikoerper, Darpp-32 antikoerper, Darpp32 antikoerper, DARPP-32 antikoerper, DARPP32 antikoerper, AU040756 antikoerper, protein phosphatase 1 regulatory inhibitor subunit 1B antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 1B antikoerper, protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog antikoerper, ppp1r1b antikoerper, PPP1R1B antikoerper, Ppp1r1b antikoerper, ppp1r1b.S antikoerper

Hintergrund:

Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ,

Aliases: DARPP32, DARPP-32

Molekulargewicht: 23 kDa

Gen-ID: 84152

HGNC: 84152