DIS3L2 Antikörper (AA 27-250)

Produktnummer ABIN1724900

Produktdetails anti-DIS3L2 Antikörper

Target: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Bindungsspezifität: AA 27-250

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DIS3L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. coli.

Klon: 6C7B2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-DIS3L2 Antikörper (ABIN1724900)

Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).

Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." in: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).

Details zu DIS3L2

Target: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Andere Bezeichnung: DIS3L2 (DIS3L2 Produkte)

Synonyme: RGD1560168 antikoerper, DIS3L2 antikoerper, DKFZp469O0522 antikoerper, FAM6A antikoerper, PRLMNS antikoerper, hDIS3L2 antikoerper, 4930429A22Rik antikoerper, 8030493P09Rik antikoerper, DIS3-like 3'-5' exoribonuclease 2 antikoerper, DIS3 like 3'-5' exoribonuclease 2 antikoerper, DIS3-like exonuclease 2 antikoerper, Dis3l2 antikoerper, DIS3L2 antikoerper, LOC100344728 antikoerper

Hintergrund:

Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. ,

Aliases: FAM6A, PRLMNS

Molekulargewicht: 99.3 kDa

Gen-ID: 129563

HGNC: 129563

Pathways: Stem Cell Maintenance