Src Antikörper (AA 10-193)

Produktnummer ABIN1724710

Produktdetails anti-Src Antikörper

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Bindungsspezifität: AA 10-193

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Src Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of SRC (aa10-193) expressed in E. coli.

Klon: 5D10C4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Src Antikörper (ABIN1724710)

Zheng, Yano, Matsumori, Nakataki, Muguruma, Yoshizumi, Sone et al.: "SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma ..." in: Clinical & experimental metastasis, Vol. 22, Issue 3, pp. 195-204, (2005) (PubMed).

Summy, Trevino, Baker, Gallick: "c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK." in: Pancreas, Vol. 31, Issue 3, pp. 263-74, (2005) (PubMed).

Details zu Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Andere Bezeichnung: SRC (Src Produkte)

Synonyme: AW259666 antikoerper, pp60c-src antikoerper, C-src1 antikoerper, CG7524 antikoerper, D-Src64B antikoerper, D-src antikoerper, DSRC64 antikoerper, DSrc antikoerper, DSrc64 antikoerper, DSrc64B antikoerper, Dm SRC1 antikoerper, DmHD-358 antikoerper, Dmel\CG7524 antikoerper, Dsrc antikoerper, Dsrc64 antikoerper, Dsrc64B antikoerper, HD-358 antikoerper, MRE5 antikoerper, SRC 64B antikoerper, Src antikoerper, Src1 antikoerper, Src64 antikoerper, c-src antikoerper, dSrc antikoerper, dsrc antikoerper, src antikoerper, src1 antikoerper, src64 antikoerper, src64B antikoerper, src64b antikoerper, ASV antikoerper, SRC1 antikoerper, c-SRC antikoerper, p60-Src antikoerper, c-Src antikoerper, PP60C-SCR antikoerper, SDR antikoerper, SRC proto-oncogene, non-receptor tyrosine kinase antikoerper, uncharacterized LOC5574802 antikoerper, proto-oncogene tyrosine-protein kinase src antikoerper, Rous sarcoma oncogene antikoerper, Src oncogene at 64B antikoerper, SRC antikoerper, LOC5574802 antikoerper, CpipJ_CPIJ010659 antikoerper, Src antikoerper, Src64B antikoerper

Substanzklasse: Viral Protein

Hintergrund:

Description: SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Aliases: ASV, SRC1, c-SRC, p60-Src

Gen-ID: 6714

HGNC: 6714

Pathways: JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling