GNA13 Antikörper (AA 21-120)

Produktnummer ABIN1715010

Produktdetails anti-GNA13 Antikörper

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNA13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein alpha 13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GNA13

Target: GNA13 (Guanine Nucleotide Binding Protein (G Protein), alpha 13 (GNA13))

Andere Bezeichnung: G protein alpha 13 (GNA13 Produkte)

Synonyme: Galpha13 antikoerper, gna13 antikoerper, wu:fe25e05 antikoerper, zgc:112436 antikoerper, Gna13 antikoerper, fj64c01 antikoerper, wu:fj64c01 antikoerper, GNA13 antikoerper, G13 antikoerper, AU024132 antikoerper, AU043124 antikoerper, G protein subunit alpha 13 antikoerper, guanine nucleotide binding protein (G protein), alpha 13a antikoerper, guanine nucleotide binding protein (G protein), alpha 13b antikoerper, guanine nucleotide binding protein, alpha 13 antikoerper, Gna13 antikoerper, gna13a antikoerper, gna13b antikoerper, GNA13 antikoerper

Hintergrund:

Synonyms: G alpha 13, GNA13, Guanine nucleotide binding protein alpha 13 subunit, GNA13_HUMAN.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified, these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67 % identity with each other and less than 45 % identity with other G Alpha subunits and are widely expressed in a broad range of tissues.

Gen-ID: 10672

Pathways: CXCR4-mediated Signaling Events