AMHR2 Antikörper (AA 21-120)

Produktnummer ABIN1714634

Produktdetails anti-AMHR2 Antikörper

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMHR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MISRII/AMHR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu AMHR2

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Andere Bezeichnung: AMHR2 (AMHR2 Produkte)

Synonyme: AMHR antikoerper, MISR2 antikoerper, MISRII antikoerper, MRII antikoerper, Misiir antikoerper, Misrii antikoerper, Mrii antikoerper, anti-Mullerian hormone receptor type 2 antikoerper, anti-Mullerian hormone type 2 receptor antikoerper, AMHR2 antikoerper, Amhr2 antikoerper

Hintergrund:

Synonyms: AMH type II receptor, AMHR2, AMHR2_HUMAN, Anti-Muellerian hormone type II receptor, Anti-Muellerian hormone type-2 receptor, MGC141312, MIS type II receptor, MISRII, MRII, Muellerian hormone type 2 receptor, Muellerian hormone type II receptor, Mullerian hormone receptor type II.

Background: MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

Gen-ID: 269