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GBA3 Antikörper (AA 151-250) (HRP)

GBA3 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1712610
  • Target Alle GBA3 Antikörper anzeigen
    GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reaktivität
    • 45
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 7
    Kaninchen
    Klonalität
    • 41
    • 4
    Polyklonal
    Konjugat
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GBA3 Antikörper ist konjugiert mit HRP
    Applikation
    • 43
    • 20
    • 16
    • 13
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Rat,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GBA3/CBG
    Isotyp
    IgG
    Top Product
    Discover our top product GBA3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
    Andere Bezeichnung
    GBA3/CBG (GBA3 Produkte)
    Synonyme
    im:6912508 antikoerper, CBG antikoerper, CBGL1 antikoerper, GLUC antikoerper, KLRP antikoerper, glucosylceramidase beta 3 antikoerper, glucosidase, beta, acid 3 (gene/pseudogene) antikoerper, glucosidase, beta, acid 3 (cytosolic) antikoerper, cytosolic beta-glucosidase antikoerper, glucosylceramidase beta 3 (gene/pseudogene) antikoerper, Gba3 antikoerper, gba3 antikoerper, GBA3 antikoerper, LOC100344458 antikoerper
    Hintergrund

    Synonyms: CBG, CBGL1, Cytosolic beta glucosidase, Cytosolic beta glucosidase like protein 1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, GBA3_HUMAN, GLUC, Glucosidase beta acid 3, Klotho related protein.

    Background: CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher?s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.

    Gen-ID
    57733
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