ACTR1 Antikörper (AA 65-160) (HRP)

Produktnummer ABIN1712384

Produktdetails anti-ACTR1 Antikörper (HRP)

Target: ACTR1 (ARP1 Actin-Related Protein 1, Centractin (ACTR1))

Bindungsspezifität: AA 65-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTR1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SKR1/ACTR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ACTR1

Target: ACTR1 (ARP1 Actin-Related Protein 1, Centractin (ACTR1))

Andere Bezeichnung: ACTR1 (ACTR1 Produkte)

Hintergrund:

Synonyms: Activin Receptor Type IA, Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, ACTR1, ACTR 1, ACTR-1, ACTR-I, ACTRI, ACVR 1, ACVR1, ACVR1_HUMAN, ACVR1A, ACVRLK 2, ACVRLK2, ALK 2, ALK-2, ALK2, FOP, Hydroxyalkyl protein kinase, Serine/threonine protein kinase receptor R1, Serine/threonine-protein kinase receptor R1, SKR 1, SKR1, TGF-B superfamily receptor type I, TGFB superfamily receptor type I, TSR-I, TSRI, TSRI.

Background: Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (16). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Gen-ID: 90