MAPK6 Antikörper (AA 21-120) (HRP)

Produktnummer ABIN1712361

Produktdetails anti-MAPK6 Antikörper (HRP)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Bindungsspezifität: AA 21-120

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK6 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAPK6/ERK3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Andere Bezeichnung: MAPK6/ERK3 (MAPK6 Produkte)

Synonyme: ERK3 antikoerper, HsT17250 antikoerper, PRKM6 antikoerper, p97MAPK antikoerper, 2610021I23Rik antikoerper, D130053K17Rik antikoerper, Erk3 antikoerper, Mapk4 antikoerper, Mapk63 antikoerper, Prkm4 antikoerper, Prkm6 antikoerper, ATMAPK6 antikoerper, ATMPK6 antikoerper, F18O19.10 antikoerper, MAP KINASE 6 antikoerper, MAP kinase 6 antikoerper, MAPK6 antikoerper, SUSERK3 antikoerper, erk3 antikoerper, p97mapk antikoerper, si:ch211-235f12.1 antikoerper, mitogen-activated protein kinase 6 antikoerper, MAP kinase 6 antikoerper, MAPK6 antikoerper, Mapk6 antikoerper, MPK6 antikoerper, mapk6 antikoerper

Hintergrund:

Synonyms: ERK-3, ERK3, ERK 3, ERK-3, Extracellular signal regulated kinase 3, Extracellular signal regulated kinase p97, Extracellular signal-regulated kinase 3, MAP kinase 6, MAP kinase isoform p97, MAPK 6, MAPK6, Mitogen activated protein kinase 6, Mitogen-activated protein kinase 6, MK06_HUMAN, p97 MAPK, p97-MAPK, PRKM6, Protein kinase mitogen activated 5, Protein kinase mitogen activated 6.

Background: Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.

Gen-ID: 5597

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Hepatitis C