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DYRK2 Antikörper (AA 425-480) (HRP)

DYRK2 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1712248
  • Target Alle DYRK2 Antikörper anzeigen
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Bindungsspezifität
    • 14
    • 11
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 425-480
    Reaktivität
    • 48
    • 31
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 60
    • 7
    • 1
    Kaninchen
    Klonalität
    • 61
    • 7
    Polyklonal
    Konjugat
    • 27
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYRK2 Antikörper ist konjugiert mit HRP
    Applikation
    • 61
    • 37
    • 32
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DYRK2
    Isotyp
    IgG
    Top Product
    Discover our top product DYRK2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Andere Bezeichnung
    DYRK2 (DYRK2 Produkte)
    Synonyme
    DYRK2 antikoerper, fc18c09 antikoerper, si:ch211-266a5.8 antikoerper, wu:fa09g03 antikoerper, wu:fc18c09 antikoerper, 1810038L18Rik antikoerper, dual specificity tyrosine phosphorylation regulated kinase 2 antikoerper, dual specificity tyrosine-phosphorylation-regulated kinase 2 antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antikoerper, DYRK2 antikoerper, CpipJ_CPIJ014802 antikoerper, dyrk2 antikoerper, Dyrk2 antikoerper
    Hintergrund

    Synonyms: 1810038L18Rik, Dual specicity tyrosine Y phosphorylation regulated kinase 2, Dual specicity tyrosine phosphorylation regulated kinase 2, Dual specicity tyrosine-phosphorylation-regulated kinase 2, DYRK2, DYRK2_HUMAN, EC 2.7.12.1, FLJ21217, FLJ21365.

    Background: Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (13). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).

    Gen-ID
    8445
    Pathways
    Regulation of Carbohydrate Metabolic Process
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