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HHAT Antikörper (AA 101-200) (Cy7)

HHAT Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy7
Produktnummer ABIN1707425
  • Target Alle HHAT Antikörper anzeigen
    HHAT (Hedgehog Acyltransferase (HHAT))
    Bindungsspezifität
    • 14
    • 9
    • 7
    • 6
    • 1
    AA 101-200
    Reaktivität
    • 31
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HHAT Antikörper ist konjugiert mit Cy7
    Applikation
    • 31
    • 14
    • 12
    • 12
    • 12
    • 12
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HHAT
    Isotyp
    IgG
    Top Product
    Discover our top product HHAT Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HHAT (Hedgehog Acyltransferase (HHAT))
    Andere Bezeichnung
    Hhat (HHAT Produkte)
    Synonyme
    RGD1311746 antikoerper, MART2 antikoerper, SKI1 antikoerper, Skn antikoerper, 2810432O22Rik antikoerper, AI462858 antikoerper, AP-2CRE antikoerper, Tg(TFAP2A-cre)1Will antikoerper, hedgehog acyltransferase antikoerper, Hhat antikoerper, HHAT antikoerper, hhat antikoerper
    Hintergrund

    Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.

    Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

    Gen-ID
    55733
    Pathways
    Hedgehog Signalweg
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