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GMPPB Antikörper (AA 111-210) (Cy5)

GMPPB Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1705146
  • Target Alle GMPPB Antikörper anzeigen
    GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 111-210
    Reaktivität
    • 39
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 3
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser GMPPB Antikörper ist konjugiert mit Cy5
    Applikation
    • 27
    • 12
    • 12
    • 12
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GMPPB
    Isotyp
    IgG
    Top Product
    Discover our top product GMPPB Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
    Andere Bezeichnung
    GMPPB (GMPPB Produkte)
    Synonyme
    MDDGA14 antikoerper, MDDGB14 antikoerper, MDDGC14 antikoerper, AI317178 antikoerper, E430010H19 antikoerper, RGD1560458 antikoerper, gmppl antikoerper, zgc:92026 antikoerper, GMPPB antikoerper, gmppb antikoerper, gmppb-a antikoerper, gmppb-b antikoerper, GDP-mannose pyrophosphorylase B antikoerper, GDP-mannose pyrophosphorylase B L homeolog antikoerper, GDP-mannose pyrophosphorylase B S homeolog antikoerper, GMPPB antikoerper, Gmppb antikoerper, gmppb antikoerper, LOAG_13550 antikoerper, gmppb.L antikoerper, gmppb.S antikoerper
    Hintergrund

    Synonyms: GDP mannose pyrophosphorylase B, GDP-mannose pyrophosphorylase B, GMPPB, GMPPB_HUMAN, GTP-mannose-1-phosphate guanylyltransferase beta, KIAA1851, Mannose 1 phosphate guanylyltransferase, Mannose-1-phosphate guanyltransferase beta.

    Background: GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events.

    Gen-ID
    29925
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