G Protein-Coupled Receptor 12 Antikörper (GPR12) (Cy5)

Details for Product anti-GPR12 Antibody No. ABIN1704905
Antigen
  • GPCR12
  • GPCR21
  • Gpcr12
  • Gpcr01
  • Gpcr20
  • Gpcr21
  • G protein-coupled receptor 12
  • G-protein coupled receptor 12
  • GPR12
  • Gpr12
Reaktivität
Human, Maus, Ratte (Rattus)
85
54
52
5
5
5
4
4
3
3
1
1
1
1
Wirt
Kaninchen
85
Klonalität
Polyklonal
Konjugat
Dieser G Protein-Coupled Receptor 12 Antikörper ist konjugiert mit Cy5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
30
25
23
15
14
7
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human G protein coupled receptor 12
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere G Protein-Coupled Receptor 12 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gpr12 (GPR12 Antibody Abstract)
Hintergrund

G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR12 is a 334 amino acid peptide that is expressed primarily in brain, particularly in regions where neuronal differentiation takes place. GPR12 is coupled to an inhibitory G protein. It positively influences differentiation and maturation of post-mitotic neurons, and it may promote the growth of neuronal precursor cells.

Subcellular location: Extracellular

Synonyms: FLJ18149, FLJ97704, G protein coupled receptor 12, G-protein coupled receptor 12, GPCR12, GPCR21, GPR 12, GPR12, GPR12_HUMAN, MGC138349, MGC138351, Probable G protein coupled receptor GPR12, GPCR GPR12.

Gen-ID 2835
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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