Chromosome 8 Open Reading Frame 45 (C8orf45) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704823
Antigen
  • C8orf45
  • 6030422M02Rik
  • minichromosome maintenance domain containing 2
  • MCMDC2
  • Mcmdc2
Reaktivität
Human, Maus, Ratte (Rattus)
24
17
17
3
3
3
2
2
2
1
Wirt
Kaninchen
23
1
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
13
12
3
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human C8orf45
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung C8orf45
Hintergrund

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf45 gene product has been provisionally designated C8orf45 pending further characterization.

Synonyms: C8orf45, Chromosome 8 open reading frame 45, FLJ25692, Minichromosome maintenance complex component like, Uncharacterized protein C8orf45, MCMD2_HUMAN.

Gen-ID 157777
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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