SP-C Propeptide Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704522
Antigen
Reaktivität
Human, Maus, Ratte (Rattus)
14
14
14
Wirt
Kaninchen
14
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
3
3
Optionen
Immunogen KLH conjugated synthetic peptide derived from human SP-C Propeptide
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Hintergrund

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Synonyms: PSP C, PSPC, Pulmonary surfactant apoprotein 2, pulmonary surfactant apoprotein PSP C, pulmonary surfactant associated protein C, pulmonary surfactant associated proteolipid SPL pVal, Pulmonary surfactant associated proteolipid SPLVal, SFTP 2, SFTP2, SFTPC, SFTPC surfactant pulmonary associated protein C, SP 5, SP C, SP5, SPC, surfactant associated protein pulmonary 2, Surfactant protein c, Surfactant pulmonary associated protein C, PSPC_HUMAN.

Gen-ID 6440
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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