TEK Antikörper (TEK Tyrosine Kinase, Endothelial) (pTyr1102) (Cy5)

Details for Product anti-TEK Antibody No. ABIN1704382
Antigen
  • TEK
  • DKFZp469E064
  • AA517024
  • Cd202b
  • Hyk
  • Tie2
  • tie-2
  • CD202B
  • TIE-2
  • TIE2
  • VMCM
  • VMCM1
  • Tie-2
  • tie2
  • TEK receptor tyrosine kinase
  • angiopoietin-1 receptor
  • TEK tyrosine kinase, endothelial
  • TEK
  • LOC100408334
  • tek
  • Tek
Epitop
pTyr1102
28
25
21
20
16
15
11
10
10
8
8
8
6
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
287
162
99
9
8
Wirt
Kaninchen
235
64
10
3
2
1
Klonalität
Polyklonal
Konjugat
Dieser TEK Antikörper ist konjugiert mit Cy5
21
14
10
8
8
8
8
8
7
7
6
4
4
4
4
4
4
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
173
128
69
52
48
22
21
19
16
12
8
6
6
3
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1102
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere TEK products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Tie2 (TEK Antibody Abstract)
Hintergrund

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.

Synonyms: p-TIE2 phospho Y1102, Angiopoietin-1 receptor, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specic receptor tyrosine kinase 2, hTIE 2, hTIE2, hTIE2, Hyk, p140 TEK, p140 TEK, Tek, tek tyrosine kinase, TEK tyrosine kinase endothelial, tek tyrosine kinase, endothelial, TIE 2, TIE2_HUMAN, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains 2, Tyrosine protein kinase receptor TEK, Tyrosine protein kinase receptor TIE 2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, Venous malformations multiple cutaneous and mucosal, VMCM 1, VMCM, VMCM1.

Gen-ID 7010
Pathways RTK Signalweg, Growth Factor Binding
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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