IGF1R Antikörper (Insulin-Like Growth Factor 1 Receptor) (Tyr1346) (Cy5)

Details for Product anti-IGF1R Antibody No. ABIN1704342
Antigen
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • IGF-IRa
  • sb:eu1090
  • wu:fi20b10
  • insulin like growth factor 1 receptor
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • insulin like growth factor 1 receptor S homeolog
  • insulin-like growth factor 1a receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • LOC100136427
  • igf1r.S
  • igf1ra
Epitop
Tyr1346
52
45
40
36
33
29
23
21
16
16
15
15
15
15
9
9
8
7
7
7
7
6
5
5
5
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
564
318
301
21
19
18
12
11
6
4
4
3
2
2
1
Wirt
Kaninchen
465
98
2
2
1
Klonalität
Polyklonal
Konjugat
Dieser IGF1R Antikörper ist konjugiert mit Cy5
23
19
16
15
14
14
14
14
14
13
8
8
8
8
8
7
6
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
359
165
152
103
89
68
61
49
15
13
8
6
3
3
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human IGF1 Receptori1/4^Tyr1346)
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere IGF1R products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Igf1r (IGF1R Antibody Abstract)
Hintergrund

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

Synonyms: IGF1 Receptor Tyr1346, IGF1 Receptor Y1346, p-IGF1 Receptor Tyr1346, p-IGF1 Receptor Tyr1346, p-IGF1 Receptor Y1346, CD221, CD221, CD221 antigen, IGF 1 receptor, IGF 1R, IGF 1R, IGF I receptor, IGF-I receptor, IGF1R, IGF1R, IGF1R_HUMAN, IGFIR, IGFIRC, IGFIRC, IGFR, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor precursor, Insulin like growth factor 1 receptor precursor, Insulin-like growth factor 1 receptor beta chain, Insulin-like growth factor I receptor, JTK13, JTK13, MGC142170, MGC142172, MGC18216.

Pathways RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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