FBXO45 Antikörper (F-Box Protein 45) (Cy5)

Details for Product anti-FBXO45 Antibody No. ABIN1704147
Antigen
  • Fbx45
  • 2610017J04Rik
  • AI463119
  • BC026799
  • zgc:65875
  • 3g27
  • F-box protein 45
  • F-box protein 45 S homeolog
  • FBXO45
  • fbxo45
  • Fbxo45
  • fbxo45.S
Reaktivität
Human, Maus, Ratte (Rattus)
20
16
16
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
20
Klonalität
Polyklonal
Konjugat
Dieser FBXO45 Antikörper ist konjugiert mit Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
7
4
3
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human FBXO45
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FBXO45 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fbxo45 (FBXO45 Antibody Abstract)
Hintergrund

Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚,B-å, and â^-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.

Gen-ID 200933
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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