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RUSC1 Antikörper (AA 281-380) (Cy3)

RUSC1 Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN1702202
  • Target Alle RUSC1 Antikörper anzeigen
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Bindungsspezifität
    • 14
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 281-380
    Reaktivität
    • 27
    • 18
    • 4
    Human, Maus
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RUSC1 Antikörper ist konjugiert mit Cy3
    Applikation
    • 20
    • 12
    • 12
    • 10
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RUSC1
    Isotyp
    IgG
    Top Product
    Discover our top product RUSC1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
    Andere Bezeichnung
    Rusc1 (RUSC1 Produkte)
    Synonyme
    NESCA antikoerper, 2210403N08Rik antikoerper, AA408288 antikoerper, RUN and SH3 domain containing 1 antikoerper, RUSC1 antikoerper, Rusc1 antikoerper
    Hintergrund

    Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.

    Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.

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