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GGA3 Antikörper (AA 51-150) (Biotin)

GGA3 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1701518
  • Target Alle GGA3 Antikörper anzeigen
    GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
    Bindungsspezifität
    • 14
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 30
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GGA3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 26
    • 13
    • 13
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GGA3
    Isotyp
    IgG
    Top Product
    Discover our top product GGA3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
    Andere Bezeichnung
    GGA3 (GGA3 Produkte)
    Synonyme
    C230037M19Rik antikoerper, mKIAA0154 antikoerper, golgi associated, gamma adaptin ear containing, ARF binding protein 3 antikoerper, Gga3 antikoerper, GGA3 antikoerper
    Hintergrund

    Synonyms: ADP ribosylation factor binding protein 3, ADP ribosylation factor binding protein GGA 3, ADP ribosylation factor binding protein GGA3, ADP-ribosylation factor-binding protein GGA3, ARF binding protein GGA 3, ARF binding protein GGA3, ARF-binding protein 3, gamma ear-containing, GGA 3, GGA3, GGA3_HUMAN, Golgi associated gamma adaptin ear containing ARF binding protein 3, Golgi localized gamma ear containing ARF binding protein 3, Golgi-localized, KIAA0154.

    Background: The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46 % sequence identity with GGA1 and 38 % with GGA2.

    Gen-ID
    23163
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