FAM134B Antikörper (AA 210-310) (Biotin)

Produktnummer ABIN1700861

Produktdetails anti-FAM134B Antikörper (Biotin)

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Bindungsspezifität: AA 210-310

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM134B Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: There is a chance that this protein will cross-react with MSL2 based on a 73 % non-sequential sequence similarity.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM134B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FAM134B

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Andere Bezeichnung: FAM134B (FAM134B Produkte)

Synonyme: JK-1 antikoerper, JK1 antikoerper, 1810015C04Rik antikoerper, AU015349 antikoerper, reticulophagy regulator 1 antikoerper, family with sequence similarity 134, member B antikoerper, RETREG1 antikoerper, Retreg1 antikoerper, Fam134b antikoerper

Hintergrund:

Synonyms: JK1, JK-1, Reticulophagy receptor FAM134B, FAM134B

Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Gen-ID: 54463

UniProt: Q9H6L5