MKLN1 Antikörper (AA 301-400) (Biotin)
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- Target Alle MKLN1 Antikörper anzeigen
- MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MKLN1 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Human,Mouse,Rat,Cow,Sheep
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MKLN1
- Isotyp
- IgG
- Top Product
- Discover our top product MKLN1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))
- Andere Bezeichnung
- MKLN1 (MKLN1 Produkte)
- Hintergrund
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Synonyms: MKLN 1, Mkln1, MKLN1_HUMAN, muskelin 1, intracellular mediator containing kelch mots, Muskelin.
Background: Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98 % amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively.
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