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FBXO45 Antikörper (AA 110-210) (Alexa Fluor 647)

FBXO45 Reaktivität: Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1698710
  • Target Alle FBXO45 Antikörper anzeigen
    FBXO45 (F-Box Protein 45 (FBXO45))
    Bindungsspezifität
    • 14
    • 2
    AA 110-210
    Reaktivität
    • 15
    • 15
    • 3
    Maus, Ratte
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXO45 Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 16
    • 12
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Sheep,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FBXO45
    Isotyp
    IgG
    Top Product
    Discover our top product FBXO45 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FBXO45 (F-Box Protein 45 (FBXO45))
    Andere Bezeichnung
    FBXO45 (FBXO45 Produkte)
    Synonyme
    Fbx45 antikoerper, 2610017J04Rik antikoerper, AI463119 antikoerper, BC026799 antikoerper, zgc:65875 antikoerper, 3g27 antikoerper, F-box protein 45 antikoerper, F-box protein 45 S homeolog antikoerper, FBXO45 antikoerper, fbxo45 antikoerper, Fbxo45 antikoerper, fbxo45.S antikoerper
    Hintergrund

    Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.

    Background: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

    Gen-ID
    200933
    UniProt
    P0C2W1
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