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CLEC12A Antikörper (AA 61-160) (Alexa Fluor 647)

CLEC12A Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1698434
  • Target Alle CLEC12A Antikörper anzeigen
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Bindungsspezifität
    • 14
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reaktivität
    • 44
    • 15
    • 11
    Human
    Wirt
    • 37
    • 6
    • 3
    • 1
    Kaninchen
    Klonalität
    • 37
    • 10
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLEC12A Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 31
    • 16
    • 12
    • 12
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CLEC12A
    Isotyp
    IgG
    Top Product
    Discover our top product CLEC12A Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Andere Bezeichnung
    CLEC12A (CLEC12A Produkte)
    Synonyme
    MGC179455 antikoerper, CLL-1 antikoerper, CLL1 antikoerper, DCAL-2 antikoerper, MICL antikoerper, D230024O04 antikoerper, KLRL1 antikoerper, Micl antikoerper, C-type lectin domain family 12 member A antikoerper, C-type lectin domain family 12, member a antikoerper, C-type lectin domain family 12, member A antikoerper, CLEC12A antikoerper, Clec12a antikoerper
    Hintergrund

    Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CL12A_HUMAN, CLEC12A, CLL-1, DCAL-2, Dendritic cell-associated lectin 2, MICL, Myeloid inhibitory C-type lectin-like receptor.

    Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer.

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