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G6PC3 Antikörper (AA 201-300) (Alexa Fluor 555)

G6PC3 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN1697246
  • Target Alle G6PC3 Antikörper anzeigen
    G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 20
    • 18
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser G6PC3 Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 19
    • 12
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human G6PC3
    Isotyp
    IgG
    Top Product
    Discover our top product G6PC3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))
    Andere Bezeichnung
    G6PC3 (G6PC3 Produkte)
    Synonyme
    SCN4 antikoerper, UGRP antikoerper, 0710001K01Rik antikoerper, AU019276 antikoerper, AU045429 antikoerper, AV128920 antikoerper, AW545836 antikoerper, glucose-6-phosphatase catalytic subunit 3 antikoerper, glucose 6 phosphatase, catalytic, 3 antikoerper, glucose 6 phosphatase catalytic subunit 3 antikoerper, G6PC3 antikoerper, G6pc3 antikoerper
    Hintergrund

    Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

    Gen-ID
    92579
    UniProt
    Q9BUM1
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