FAM212B Antikörper (AA 1-100) (Alexa Fluor 555)

Produktnummer ABIN1697217

Produktdetails anti-FAM212B Antikörper (Alexa Fluor 555)

Target: FAM212B (Family with Sequence Similarity 212, Member B (FAM212B))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM212B Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf183

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FAM212B

Target: FAM212B (Family with Sequence Similarity 212, Member B (FAM212B))

Andere Bezeichnung: C1orf183 (FAM212B Produkte)

Synonyme: C1orf183 antikoerper, C3H1orf183 antikoerper, RGD1306526 antikoerper, 6530418L21Rik antikoerper, family with sequence similarity 212 member B antikoerper, family with sequence similarity 212, member B antikoerper, FAM212B antikoerper, Fam212b antikoerper

Hintergrund:

Synonyms: C1orf183, CA183_HUMAN, Chromosome 1 open reading frame 183, FLJ31105, Uncharacterized protein C1orf183.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf183 gene product has been provisionally designated C1orf183 pending further characterization. There are two isoforms of C1orf183 that are produced as a result of alternative splicing events.

Gen-ID: 55924