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FNBP1 Antikörper (AA 331-430) (Alexa Fluor 488)

FNBP1 Reaktivität: Kugelfisch, Xenopus laevis WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN1695585
  • Target Alle FNBP1 Antikörper anzeigen
    FNBP1 (Formin Binding Protein 1 (FNBP1))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 331-430
    Reaktivität
    • 14
    • 14
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Kugelfisch, Xenopus laevis
    Wirt
    • 25
    • 1
    • 1
    Kaninchen
    Klonalität
    • 26
    • 1
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FNBP1 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 25
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Kugelfisch, Xenopus laevis
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Zebrafish
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FBP17
    Isotyp
    IgG
    Top Product
    Discover our top product FNBP1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FNBP1 (Formin Binding Protein 1 (FNBP1))
    Andere Bezeichnung
    FBP17 (FNBP1 Produkte)
    Synonyme
    MGC122623 antikoerper, MGC146466 antikoerper, FBP17 antikoerper, 1110057E06Rik antikoerper, 2210010H06Rik antikoerper, FBP1 antikoerper, Fbp17 antikoerper, formin binding protein 1 antikoerper, formin binding protein 1 L homeolog antikoerper, FNBP1 antikoerper, fnbp1 antikoerper, Fnbp1 antikoerper, fnbp1.L antikoerper
    Hintergrund

    Synonyms: FBP1, FBP17, FNBP1, FNBP1_HUMAN, Formin binding protein 1, Formin binding protein 17, Formin-binding protein 1, Formin-binding protein 17, hFBP17, KIAA0554, MGC126804.

    Background: FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.

    Gen-ID
    23048
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