C1orf174 Antikörper (AA 161-243) (Alexa Fluor 488)

Produktnummer ABIN1695547

Produktdetails anti-C1orf174 Antikörper (Alexa Fluor 488)

Target: C1orf174 (Chromosome 1 Open Reading Frame 174 (C1orf174))

Bindungsspezifität: AA 161-243

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf174 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf174

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu C1orf174

Target: C1orf174 (Chromosome 1 Open Reading Frame 174 (C1orf174))

Andere Bezeichnung: C1orf174 (C1orf174 Produkte)

Synonyme: C1orf174 antikoerper, RP13-531C17.2 antikoerper, chromosome 21 C1orf174 homolog antikoerper, chromosome 1 open reading frame 174 antikoerper, chromosome 16 C1orf174 homolog antikoerper, C21H1orf174 antikoerper, C1orf174 antikoerper, C16H1orf174 antikoerper

Hintergrund:

Synonyms: C1orf174, CA174_HUMAN, Chromosome 1 open reading frame 174, Hypothetical protein LOC339448, OTTHUMP00000003854, RP13-531C17.2, UPF0688 protein C1orf174.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf174 gene product has been provisionally designated C1orf174 pending further characterization.

Gen-ID: 339448