KNDC1 Antikörper (AA 1601-1749) (Alexa Fluor 488)

Produktnummer ABIN1695334

Produktdetails anti-KNDC1 Antikörper (Alexa Fluor 488)

Target: KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))

Bindungsspezifität: AA 1601-1749

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNDC1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KNDC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KNDC1

Target: KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))

Andere Bezeichnung: KNDC1 (KNDC1 Produkte)

Synonyme: C10orf23 antikoerper, RASGEF2 antikoerper, bB439H18.3 antikoerper, 2410012C07Rik antikoerper, B830014K08Rik antikoerper, VKIND antikoerper, very-kind antikoerper, RGD1565261 antikoerper, kinase non-catalytic C-lobe domain containing 1 antikoerper, kinase non-catalytic C-lobe domain (KIND) containing 1 antikoerper, protein very KIND antikoerper, KNDC1 antikoerper, Kndc1 antikoerper, LOC536342 antikoerper

Hintergrund:

Synonyms: Cerebral protein 9, FLJ25027, hucep-9, KIAA1768, Kinase non-catalytic C-lobe domain-containing protein 1, KIND domain-containing protein 1, KNDC1, Protein very KIND, Ras-GEF domain-containing family member 2, RASGEF2, VKIND, VKIND_HUMAN, bB439H18.3, C10orf23.

Background: KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Gen-ID: 85442