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ECAT1 Antikörper (AA 1-100) (Alexa Fluor 350)

KHDC3L Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693005
  • Target Alle ECAT1 (KHDC3L) Antikörper anzeigen
    ECAT1 (KHDC3L) (KH Domain Containing 3-Like, Subcortical Maternal Complex Member (KHDC3L))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    AA 1-100
    Reaktivität
    Human
    Wirt
    • 30
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ECAT1 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 16
    • 16
    • 14
    • 14
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Ecat1
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ECAT1 (KHDC3L) (KH Domain Containing 3-Like, Subcortical Maternal Complex Member (KHDC3L))
    Andere Bezeichnung
    Ecat1 (KHDC3L Produkte)
    Synonyme
    C6orf221 antikoerper, ECAT1 antikoerper, HYDM2 antikoerper, KH domain containing 3 like, subcortical maternal complex member antikoerper, KHDC3L antikoerper
    Hintergrund

    Synonyms: C6orf221, Chromosome 6 open reading frame 221, ES cell-associated transcript 1 protein, HYDM2, KHD3L_HUMAN, KHDC3-like protein, KHDC3L.

    Background: ECAT1 (ES cell-associated transcript 1 protein) is a 217 amino acid protein that belongs to the KHDC1 family. The ECAT1 protein contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA. Expression of ECAT1 appears to be maximal in germinal vesicle oocytes, it tails off through metaphase II oocytes and is undetectable following the completion of the oocyte to embryo transition. Specifically expressed in the oocytes, recent studies suggest that ECAT1 may function as a regulator of genomic imprinting in the oocyte. Defects in ECAT1 are the cause of hydatidiform mole recurrent type 2 (HYDM2), a disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. HYDM2 leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi.

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