HESX Homeobox 1 Antikörper (AA 51-150) (Alexa Fluor 350)

Produktnummer ABIN1692763

Produktdetails anti-HESX Homeobox 1 Antikörper (Alexa Fluor 350)

Target: HESX Homeobox 1 (HESX1)

Bindungsspezifität: AA 51-150

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HESX Homeobox 1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HESX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HESX Homeobox 1

Target: HESX Homeobox 1 (HESX1)

Andere Bezeichnung: HESX1 (HESX1 Produkte)

Synonyme: HES-1 antikoerper, Rpx antikoerper, RGD1563858 antikoerper, ANF antikoerper, CPHD5 antikoerper, RPX antikoerper, XANF-2 antikoerper, Xanf antikoerper, Xanf-1 antikoerper, Xanf1 antikoerper, Xanf2 antikoerper, anf2 antikoerper, anf2-A antikoerper, rpx antikoerper, anf1 antikoerper, hesx1 antikoerper, xanf-1 antikoerper, HESX1 antikoerper, GANF antikoerper, Anf antikoerper, danf antikoerper, zanf antikoerper, homeobox gene expressed in ES cells antikoerper, HESX homeobox 1 antikoerper, HESX homeobox 1 S homeolog antikoerper, HESX homeobox 1 L homeolog antikoerper, Hesx1 antikoerper, HESX1 antikoerper, hesx1.S antikoerper, hesx1.L antikoerper, hesx1 antikoerper

Hintergrund:

Synonyms: NULL

Background: The homeobox protein, HESX1, which is also known as Rathke?s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.