UQCRC1 Antikörper (AA 156-480)

Produktnummer ABIN1683221

Produktdetails anti-UQCRC1 Antikörper

Target: UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))

Bindungsspezifität: AA 156-480

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UQCRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LEDSQIEKER DVILREMQEN DASMRDVVFN YLHATAFQGT PLAQAVEGPS ENVRKLSRAD LTEYLSTHYK APRMVLAAAG GVEHQQLLDL AQKHLGGIPW TYAEDAVPTL TPCRFTGSEI RHRDDALPFA HVAIAVEGPG WASPDNVALQ VANAIIGHYD CTYGGGVHLS SPLASGAVAN KLCQSFQTFS ICYAETGLLG AHFVCDRMKI DDMMFVLQGQ WMRLCTSATE SEVARGKNIL RNALVSHLDG TTPVCEDIGR SLLTYGRRIP LAEWESRIAE VDASVVREIC SKYIYDQCPA VAGYGPIEQL PDYNRIRSGM FWLRF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UQCRC1

Target: UQCRC1 (Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1))

Andere Bezeichnung: UQCRC1 (UQCRC1 Produkte)

Synonyme: MGC53748 antikoerper, zgc:73404 antikoerper, zgc:85750 antikoerper, 1110032G10Rik antikoerper, D3S3191 antikoerper, QCR1 antikoerper, UQCR1 antikoerper, ubiquinol-cytochrome c reductase core protein 1 L homeolog antikoerper, ubiquinol-cytochrome c reductase core protein 1 antikoerper, ubiquinol-cytochrome c reductase core protein I antikoerper, cytochrome b-c1 complex subunit 1, mitochondrial antikoerper, uqcrc1.L antikoerper, uqcrc1 antikoerper, UQCRC1 antikoerper, LOC100020379 antikoerper, LOC100074417 antikoerper, LOC100347571 antikoerper, LOC100413740 antikoerper, LOC100452425 antikoerper, Uqcrc1 antikoerper

Hintergrund: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity. The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties (By similarity. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS/subunit 9 when incorporated into complex III (Probable.,UQCRC1,D3S3191,QCR1,UQCR1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,UQCRC1

Molekulargewicht: 52 kDa

Gen-ID: 7384

UniProt: P31930