KAP1 Antikörper (AA 576-835)

Produktnummer ABIN1683037

Produktdetails anti-KAP1 Antikörper

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Bindungsspezifität: AA 576-835

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: PVLMALAEGP GAEGPRLASP SGSTSSGLEV VAPEGTSAPG GGPGTLDDSA TICRVCQKPG DLVMCNQCEF CFHLDCHLPA LQDVPGEEWS CSLCHVLPDL KEEDGSLSLD GADSTGVVAK LSPANQRKCE RVLLALFCHE PCRPLHQLAT DSTFSLDQPG GTLDLTLIRA RLQEKLSPPY SSPQEFAQDV GRMFKQFNKL TEDKADVQSI IGLQRFFETR MNEAFGDTKF SAVLVEPPPM SLPGAGLSSQ ELSGGPGDGP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 576-835 of human KAP1/KAP1/TRIM28 (NP_005753.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:3000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-KAP1 Antikörper (ABIN1683037)

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." in: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Details zu KAP1

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Andere Bezeichnung: TRIM28 (TRIM28 Produkte)

Synonyme: KAP1 antikoerper, RNF96 antikoerper, TF1B antikoerper, TIF1B antikoerper, TRIM28 antikoerper, kap1 antikoerper, rnf96 antikoerper, tf1b antikoerper, tif1b antikoerper, AA408787 antikoerper, KAP-1 antikoerper, KRIP-1 antikoerper, Tif1b antikoerper, Tif1beta antikoerper, Kap1 antikoerper, Krip1 antikoerper, TIF1BETA antikoerper, tripartite motif containing 28 antikoerper, tripartite motif containing 28 L homeolog antikoerper, tripartite motif-containing 28 antikoerper, TRIM28 antikoerper, trim28.L antikoerper, Trim28 antikoerper

Hintergrund: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.,KAP1,PPP1R157,RNF96,TF1B,TIF1B,TRIM28,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,TRIM28

Molekulargewicht: 79 kDa/88 kDa

Gen-ID: 10155

UniProt: Q13263

Pathways: Hedgehog Signalweg, Positive Regulation of Response to DNA Damage Stimulus