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7-Sep (AA 307-436) Antikörper

Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1682655
  • Target
    7-Sep
    Bindungsspezifität
    • 1
    • 1
    • 1
    AA 307-436
    Reaktivität
    • 4
    • 1
    • 1
    Human
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 3
    • 1
    Unkonjugiert
    Applikation
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    NYRSRKLAAV TYNGVDNNKN KGQLTKSPLA QMEEERREHV AKMKKMEMEM EQVFEMKVKE KVQKLKDSEA ELQRRHEQMK KNLEAQHKEL EEKRRQFEDE KANWEAQQRI LEQQNSSRTL EKNKKKGKIF
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 307-436 of human Septin 7 (NP_001011553.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    7-Sep
    Hintergrund
    This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.,SEPT7,CDC10,CDC3,NBLA02942,SEPT7A,septin-7,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,7-Sep
    Molekulargewicht
    50 kDa
    Gen-ID
    989
    UniProt
    Q16181
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