CYP24A1 Antikörper (AA 36-448)

Produktnummer ABIN1679472

Produktdetails anti-CYP24A1 Antikörper

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Bindungsspezifität: AA 36-448

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP24A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PQPREVPVCP LTAGGETQNA AALPGPTSWP LLGSLLQILW KGGLKKQHDT LVEYHKKYGK IFRMKLGSFE SVHLGSPCLL EALYRTESAY PQRLEIKPWK AYRDYRKEGY GLLILEGEDW QRVRSAFQKK LMKPGEVMKL DNKINEVLAD FMGRIDELCD ERGHVEDLYS ELNKWSFESI CLVLYEKRFG LLQKNAGDEA VNFIMAIKTM MSTFGRMMVT PVELHKSLNT KVWQDHTLAW DTIFKSVKAC IDNRLEKYSQ QPSADFLCDI YHQNRLSKKE LYAAVTELQL AAVETTANSL MWILYNLSRN PQVQQKLLKE IQSVLPENQV PRAEDLRNMP YLKACLKESM RLTPSVPFTT RTLDKATVLG EYALPKGIVR KYDIQATDNE PVEMLHSGTL VPSRELPIAF CQR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP24A1

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Andere Bezeichnung: CYP24A1 (CYP24A1 Produkte)

Synonyme: CP24 antikoerper, CYP24 antikoerper, HCAI antikoerper, P450-CC24 antikoerper, 24-OHase antikoerper, Cyp24 antikoerper, 25-hydroxyvitaminD324-hydroxylase antikoerper, VITD12 antikoerper, CP450CC24 antikoerper, cytochrome P450 family 24 subfamily A member 1 antikoerper, cytochrome P450, family 24, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 24, subfamily A, polypeptide 1 antikoerper, CYP24A1 antikoerper, Cyp24a1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CYP24A1,CP24,CYP24,HCAI,HCINF1,P450-CC24,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Lipid Metabolism,Cytochromes,Lipases,Cardiovascular,Lipids,CYP24A1

Molekulargewicht: 43 kDa/51 kDa/58 kDa

Gen-ID: 1591

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D