CKMT1A Antikörper (AA 258-417)

Produktnummer ABIN1679244

Produktdetails anti-CKMT1A Antikörper

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Bindungsspezifität: AA 258-417

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FLIWVNEEDH TRVISMEKGG NMKRVFERFC RGLKEVERLI QERGWEFMWN ERLGYILTCP SNLGTGLRAG VHIKLPLLSK DSRFPKILEN LRLQKRGTGG VDTAATGGVF DISNLDRLGK SEVELVQLVI DGVNYLIDCE RRLERGQDIR IPTPVIHTKH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 258-417 of human CKMT1A (NP_001015001.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CKMT1A

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Andere Bezeichnung: CKMT1A (CKMT1A Produkte)

Synonyme: CKMT1 antikoerper, Mt-CK antikoerper, ScCKmit antikoerper, UbCKmit antikoerper, mi-CK antikoerper, Ckmt1 antikoerper, CKMT1B antikoerper, Mia-CK antikoerper, U-MtCK antikoerper, creatine kinase, mitochondrial 1A antikoerper, creatine kinase U-type, mitochondrial-like antikoerper, creatine kinase, mitochondrial 1, ubiquitous antikoerper, creatine kinase U-type, mitochondrial antikoerper, CKMT1A antikoerper, LOC100228000 antikoerper, Ckmt1 antikoerper, LOC100725326 antikoerper

Hintergrund: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1A,CKMT1,U-MtCK,mia-CK,Signal Transduction,Kinase,CKMT1A

Molekulargewicht: 47 kDa/50 kDa

Gen-ID: 548596

UniProt: P12532