Cyclin B2 Antikörper (AA 1-100)

Produktnummer ABIN1679041

Produktdetails anti-Cyclin B2 Antikörper

Target: Cyclin B2 (CCNB2)

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MALLRRPTVS SDLENIDTGV NSKVKSHVTI RRTVLEEIGN RVTTRAAQVA KKAQNTKVPV QPTKTTNVNK QLKPTASVKP VQMEKLAPKG PSPTPEDVSM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Cyclin B2 (NP_004692.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Cyclin B2 Antikörper (ABIN1679041)

Sun, Xie, Xu, Cai, Zhang, Cui, Zheng, Zhou: "Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway." in: Redox biology, Vol. 14, pp. 338-353, (2018) (PubMed).

Li, Wei, Hu, Zhang, Li, Wan, Zhang, Yao: "Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats." in: Frontiers in cellular neuroscience, Vol. 11, pp. 368, (2017) (PubMed).

Details zu Cyclin B2

Target: Cyclin B2 (CCNB2)

Andere Bezeichnung: CCNB2 (CCNB2 Produkte)

Synonyme: HsT17299 antikoerper, CycB2 antikoerper, sb:cb303 antikoerper, cycB2 antikoerper, LOC100136691 antikoerper, C-B2 antikoerper, cyclinb2 antikoerper, hst17299 antikoerper, LOC100282653 antikoerper, cyclin B2 antikoerper, cyclin B2 S homeolog antikoerper, CCNB2 antikoerper, Ccnb2 antikoerper, ccnb2 antikoerper, LOC100136691 antikoerper, LOC100282653 antikoerper, ccnb2.S antikoerper

Hintergrund: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.,CCNB2,HsT17299,cyclin B2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G2/M DNA Damage Checkpoint,CCNB2

Molekulargewicht: 45 kDa

Gen-ID: 9133

UniProt: O95067

Pathways: Zellzyklus, M Phase