HDAC5 Antikörper (Internal Region)

Produktnummer ABIN1607888

Produktdetails anti-HDAC5 Antikörper

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with HDAC5 from other sources has not been determined.

Reinheit: Anti-HDAC5 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC5. A BLAST analysis was used to suggest cross-reactivity with Human based on 100 % sequence homology.

Endotoxin-Niveau: Low Endotoxin : No

Immunogen: HDAC5 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human HDAC5.
Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise: Anti-HDAC5 antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~124 kDa corresponding to the appropriate cell lysate or extract.
ELISA Dilution: 1:20.000 - 1:60.000
Immunohistochemistry Dilution: 1:100-1:500
IF Microscopy Dilution: 1:100-1:500
Western Blot Dilution: 0.2 µg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.12 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: Expiration date is six (6) months from date of opening.

Details zu HDAC5

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Andere Bezeichnung: HDAC5 (HDAC5 Produkte)

Synonyme: HD5 antikoerper, NY-CO-9 antikoerper, AI426555 antikoerper, Hdac4 antikoerper, mHDA1 antikoerper, mKIAA0600 antikoerper, ATHDA5 antikoerper, HDA5 antikoerper, MAF19.7 antikoerper, MAF19_7 antikoerper, histone deacetylase 5 antikoerper, histone deacetylase 5 antikoerper, HDAC5 antikoerper, Hdac5 antikoerper, HDA05 antikoerper, hdac5 antikoerper

Hintergrund: HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions. Anti-HDAC5 antibodies are ideal for researchers interested in Breast Cancer, Cancer, Cell Cycle and Replication, Chromatin Research, Epigenetics, and Histone Deacetylases research. Synonyms: Antigen NY-CO-9, EC 3.5.1.98, FLJ90614, HD5, histone deacetylase 5, KIAA0600, NY-CO-9

Gen-ID: 10014

NCBI Accession: NP_005465

UniProt: Q9UQL6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process