EGFL7 Antikörper

Produktnummer ABIN1589899

Produktdetails anti-EGFL7 Antikörper

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGFL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität: Recombinant human EGFL-7 C-Terminus

Produktmerkmale: Chromosomal location: 9q34.3
Produced from sera of rabbits immunised with highly pure recombinant human VE-Statin/EGFL-7.

Aufreinigung: Anti-human VE-Statin/EGFL-7 was purified by Protein-A chromatography.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: use 2-5 µg/mL

Kommentare:

Rabbit IG Polyclonal Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

Haltbarkeit: 6 months

Details zu EGFL7

Target: EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))

Andere Bezeichnung: VE-Statin/EGFL-7 (EGFL7 Produkte)

Synonyme: egfl7 antikoerper, MGC53105 antikoerper, EGFL7 antikoerper, zgc:136669 antikoerper, zgc:152804 antikoerper, zneu1 antikoerper, xegfl7 antikoerper, MGC147423 antikoerper, VE-statin antikoerper, Zneu1 antikoerper, NEU1 antikoerper, RP11-251M1.2 antikoerper, VE-STATIN antikoerper, ZNEU1 antikoerper, EGF like domain multiple 7 S homeolog antikoerper, EGF like domain multiple 7 antikoerper, EGF-like-domain, multiple 7 antikoerper, EGF-like domain 7 antikoerper, egfl7.S antikoerper, EGFL7 antikoerper, egfl7 antikoerper, Egfl7 antikoerper

Hintergrund: EGFL7 (VE-Statin) is an ∼ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms: EGFL7, NEU1, ZNEU1, VE-STATIN, RP11-251M1.2, NOTCH4-like protein, Vascular endothelial statin

NCBI Accession: NP_057299, NM_016215

UniProt: Q9UHF1