FAM193B Antikörper (N-Term)
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- Target Alle FAM193B Produkte
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FAM193B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), ELISA
- Spezifität
- At least two isoforms of FAM193B are known to exist, this antibody will detect both isoforms.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
- Isotyp
- IgG
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- Applikationshinweise
- FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
- Kommentare
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(NT) Family with sequence similarity 193 member B
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- FAM193B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Haltbarkeit
- 12 months
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- Target
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
- Andere Bezeichnung
- FAM193B (FAM193B Produkte)
- Synonyme
- IRIZIO antikoerper, Kiaa1931 antikoerper, family with sequence similarity 193 member B antikoerper, family with sequence similarity 193, member B antikoerper, FAM193B antikoerper, Fam193b antikoerper
- Hintergrund
- FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
- Molekulargewicht
- 99 kDa
- Gen-ID
- 54540
- UniProt
- Q96PV7
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