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FAM193B Antikörper (N-Term)

FAM193B Reaktivität: Human WB, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1587943
  • Target Alle FAM193B Produkte
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    Bindungsspezifität
    • 3
    • 1
    N-Term
    Reaktivität
    Human
    Wirt
    • 3
    Kaninchen
    Klonalität
    • 3
    Polyklonal
    Konjugat
    • 3
    Dieser FAM193B Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA
    Spezifität
    At least two isoforms of FAM193B are known to exist, this antibody will detect both isoforms.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
    Isotyp
    IgG
  • Applikationshinweise
    FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
    Kommentare

    (NT) Family with sequence similarity 193 member B

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Lagerung
    4 °C
    Informationen zur Lagerung
    FAM193B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    Haltbarkeit
    12 months
  • Target
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    Andere Bezeichnung
    FAM193B (FAM193B Produkte)
    Synonyme
    IRIZIO antikoerper, Kiaa1931 antikoerper, family with sequence similarity 193 member B antikoerper, family with sequence similarity 193, member B antikoerper, FAM193B antikoerper, Fam193b antikoerper
    Hintergrund
    FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
    Molekulargewicht
    99 kDa
    Gen-ID
    54540
    UniProt
    Q96PV7
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