MMP2 Antikörper (Matrix Metalloproteinase 2) (N-Term)

Details for Product anti-MMP2 Antibody No. ABIN1582259, Anbieter: Anmelden zum Anzeigen
Antigen
  • 2-MMP
  • CG1794
  • DM2-MMP
  • Dm2-MMP
  • Dmel\\CG1794
  • MMP2
  • anon-WO0118547.84
  • dm-2MMP
  • dmmp2
  • l(2)02353
  • mmp2
  • wu:fa99h12
  • wu:fk89d01
  • fgmmp-2
  • Mmp-2
  • LOC100135793
  • Clg4a
  • GelA
  • MMP-2
  • CLG4
  • CLG4A
  • MMP-II
  • MONA
  • TBE-1
  • matrix metallopeptidase 2
  • Matrix metalloproteinase 2
  • matrix metalloproteinase 2
  • matrix metalloproteinase-2
  • MMP2
  • Mmp2
  • mmp2
  • LOC657982
  • LOC100135793
Epitop
N-Term
20
19
16
16
15
15
12
11
9
8
8
7
6
6
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Human, Maus, Schwein, Ratte (Rattus), Schaf
394
175
167
32
21
18
14
14
9
7
5
5
5
5
4
4
2
2
1
1
1
1
Wirt
Kaninchen
223
186
3
2
2
1
Klonalität
Polyklonal
Konjugat
Dieser MMP2 Antikörper ist unkonjugiert
20
15
13
9
9
7
6
6
5
5
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
1
1
1
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
314
162
98
98
88
80
71
53
42
39
6
5
3
3
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MMP-2.
Kreuzreaktivität Rind (Kuh), Maus, Schwein, Ratte (Rattus), Schaf
Reinigung Antibody was purified by Protein-G affinity chromatography.
Andere Bezeichnung MMP-2 (MMP2 Antibody Abstract)
Hintergrund

Alternate Names: 72 kDa type IV collagenase, 72 kDa gelatinase, Matrix metalloproteinase-2, MMP-2, Gelatinase A, TBE-1, MMP2, CLG4A

Description: Matrix metalloproteinase protein family (MMP) is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in diseases such as arthritis and metastasis. Most MMPs are secreted as inactive precursors which are activated upon cleavage by extracellular proteinases. MMP-2 is an enzyme that degrades gelatin type I and collagen types IV, V, VII and X, and KiSS1. MMP-2 is also a ligand for the integrin alpha-V/beta-3. Defects in MMP-2 are the cause of multicentric osteolysis nodulosis and arthropathy (MONA), and Winchester syndrome, both characterized by excessive destruction and resorption of bones.

UniProt P08253
Pathways Activation of Innate immune Response
Applikations-hinweise E: 1:500-1:1,000, WB: 1:200-1:500, IHC: 1:200-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL (1 mg/mL) of PBS pH 7.4 with 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handhabung Minimize freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Haltbarkeit 12 months
Bilder des Herstellers
 image for anti-Matrix Metalloproteinase 2 (MMP2) (N-Term) antibody (ABIN1582259) MMP-2 staining in human stomach cancer. Paraffin-embedded human stomach cancer is sta...
Produkt verwendet in: Zhu, Liu, Wu, Liu: "Activin A regulates proliferation, invasion and migration in osteosarcoma cells." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4501-7, 2015 (PubMed).

de Oliveira, Baldo, Mayer, Martinelli, Meurer, Giugliani, Matte, Xavier: "Characterization of joint disease in mucopolysaccharidosis type I mice." in: International journal of experimental pathology, Vol. 94, Issue 5, pp. 305-11, 2013 (PubMed).

Li, Lin, Huang, Hong, Chen, You, Li: "Zoledronic acid inhibits proliferation and impairs migration and invasion through downregulating VEGF and MMPs expression in human nasopharyngeal carcinoma cells." in: Medical oncology (Northwood, London, England), Vol. 29, Issue 2, pp. 714-20, 2012 (PubMed).

Riau, Wong, Lan, Finger, Chaurasia, Hou, Chen, Yu, Tong: "Aberrant DNA methylation of matrix remodeling and cell adhesion related genes in pterygium." in: PLoS ONE, Vol. 6, Issue 2, pp. e14687, 2011 (PubMed).

Seet, Su, Barathi, Lee, Poh, Heng, Manser, Vithana, Aung, Weaver, Sage, Wong: "SPARC deficiency results in improved surgical survival in a novel mouse model of glaucoma filtration surgery." in: PLoS ONE, Vol. 5, Issue 2, pp. e9415, 2010 (PubMed).

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