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Endonuclease G Antikörper (AA 200-250)

ENDOG Reaktivität: Human, Maus, Ratte WB, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1574189
  • Target Alle Endonuclease G (ENDOG) Antikörper anzeigen
    Endonuclease G (ENDOG)
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-250
    Reaktivität
    • 44
    • 30
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 52
    • 9
    Kaninchen
    Klonalität
    • 45
    • 16
    Polyklonal
    Konjugat
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Endonuclease G Antikörper ist unkonjugiert
    Applikation
    • 44
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    EndoG Antibody detects endogenous levels of mouse EndoG. Predicted to react with rat EndoG protein according to sequence homology.Positive Control: Ramos, mouse kidney
    Kreuzreaktivität (Details)
    EndoG Antibody detects endogenous levels of mouse EndoG. Predicted to react with rat EndoG protein according to sequence homology.Positive Control: Ramos, mouse kidney
    Aufreinigung
    Immunoaffinity chromatography
    Immunogen
    KLH-coupled synthetic peptide within AA 200–250 of human EndoG
    Isotyp
    IgG
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    Discover our top product ENDOG Primärantikörper
  • Applikationshinweise
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
    Western blot: 0.5-1 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther applications: user-optimized
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • Target
    Endonuclease G (ENDOG)
    Andere Bezeichnung
    EndoG (ENDOG Produkte)
    Synonyme
    CG8862 antikoerper, Dmel\\CG8862 antikoerper, Tb08.10J17.140 antikoerper, Tb08.10J17.90 antikoerper, TBC1D13 antikoerper, endog antikoerper, ENDOG antikoerper, wu:fb79c08 antikoerper, zgc:110020 antikoerper, Endonuclease G antikoerper, endonuclease G antikoerper, putative endonuclease G antikoerper, endonuclease G, mitochondrial antikoerper, endonuclease G L homeolog antikoerper, EndoG antikoerper, Tc00.1047053506867.10 antikoerper, Tb927.8.4040 antikoerper, Tb927.8.4090 antikoerper, LBRM_10_0750 antikoerper, LMJF_10_0610 antikoerper, NAEGRDRAFT_78507 antikoerper, ENDOG antikoerper, endog antikoerper, eNDOG antikoerper, LOC100529218 antikoerper, Endog antikoerper, endog.L antikoerper
    Hintergrund
    Endo G is an endonuclease that cleaves DNA at GC tracts. It is capable of generating the RNA primers required by DNA polymerase gamma to initiate the replication of mitochondrial DNA. EndoG is a mitochondrion-specific nuclease that cleaves chromatin DNA during apoptosis.Rabbit EndoG Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 200-50 of human EndoG (Swiss Prot: Q14249).
    Pathways
    Apoptose
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