Calnexin Antikörper (C-Term)

Produktnummer ABIN1574057

Produktdetails anti-Calnexin Antikörper

Target: Calnexin (CANX)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Orang-Utan

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Spezifität: Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.

Kreuzreaktivität (Details): Calnexin Antibody, pAb, Rabbit detects endogenous levels of human and mouse calnexin protein. Sequence homology predicts that it will also react with rat, bovine, canine, and Sumatran orangutan calnexin.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide (KLH-coupled) from carboxyl terminal of human calnexin .

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther applications: user-optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Referenzen für anti-Calnexin Antikörper (ABIN1574057)

Li, Muma: "Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT?A receptor: characterization and subcellular distribution of sumoylated 5-HT?A receptors." in: Psychoneuroendocrinology, Vol. 38, Issue 11, pp. 2542-53, (2013) (PubMed).

Weber, Chen, Rowin, Mertens, Galvan, Zhi, Dealing, Roman, Banga, Tan, Luo, Samuel: "Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation." in: Journal of bacteriology, Vol. 195, Issue 17, pp. 3914-24, (2013) (PubMed).

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin (CANX Produkte)

Synonyme: CNX antikoerper, IP90 antikoerper, P90 antikoerper, 1110069N15Rik antikoerper, AI988026 antikoerper, Cnx antikoerper, D11Ertd153e antikoerper, canx antikoerper, clgn antikoerper, clnx antikoerper, cnx antikoerper, PP90 antikoerper, zgc:63524 antikoerper, wu:fe06b12 antikoerper, CANX antikoerper, calnexin antikoerper, CalNeXin antikoerper, calnexin L homeolog antikoerper, CANX antikoerper, Canx antikoerper, cnx-1 antikoerper, canx.L antikoerper, canx antikoerper, LOC100283947 antikoerper

Hintergrund: Calnexin is calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may be involved in assisting protein assembly or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the ER quality control apparatus via the retention of incorrectly folded proteins.Calnexin Antibody, pAb, Rabbit is developed in rabbit hosts using a KLH-coupled synthetic peptide from carboxyl terminal of human calnexin protein (Swiss Prot: P27824).

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis