HERPUD1 Antikörper (N-Term)

Produktnummer ABIN1539462

Produktdetails anti-HERPUD1 Antikörper

Target: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Bindungsspezifität: AA 55-83, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERPUD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.

Klon: RB36972

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: HERPUD1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu HERPUD1

Target: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Andere Bezeichnung: HERPUD1 (HERPUD1 Produkte)

Synonyme: herpud1-a antikoerper, herp antikoerper, herpud1 antikoerper, mif1 antikoerper, sup antikoerper, HERPUD1 antikoerper, zgc:114134 antikoerper, HERP antikoerper, Mif1 antikoerper, SUP antikoerper, Herp antikoerper, Mifl antikoerper, Sup antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 antikoerper, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 antikoerper, herpud1.S antikoerper, herpud1.L antikoerper, herpud1 antikoerper, HERPUD1 antikoerper, Herpud1 antikoerper

Hintergrund: The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].

Molekulargewicht: 43720

Gen-ID: 9709

NCBI Accession: NP_001010989, NP_001259032, NP_055500

UniProt: Q15011

Pathways: ER-Nucleus Signaling