This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
fj43a07 antikoerper, zgc:56037 antikoerper, wu:fj43a07 antikoerper, MGC81035 antikoerper, rcbtb1 antikoerper, CLLD7 antikoerper, CLLL7 antikoerper, GLP antikoerper, RP11-185C18.1 antikoerper, 5430409I18Rik antikoerper, AW111883 antikoerper, RCC1 and BTB domain containing protein 1 antikoerper, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antikoerper, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 S homeolog antikoerper, RCC1 and BTB domain-containing protein 1 antikoerper, Rcbtb1 antikoerper, RCBTB1 antikoerper, rcbtb1 antikoerper, rcbtb1.S antikoerper, LOC100470400 antikoerper
Hintergrund
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.