DPF1 Antikörper (AA 220-247)

Produktnummer ABIN1538107

Produktdetails anti-DPF1 Antikörper

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Bindungsspezifität: AA 220-247

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DPF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-247 amino acids from the Central region of human DPF1.

Klon: RB37854

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DPF1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu DPF1

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Andere Bezeichnung: DPF1 (DPF1 Produkte)

Synonyme: zgc:110104 antikoerper, DPF1 antikoerper, req antikoerper, xReq antikoerper, neud4 antikoerper, requiem antikoerper, neuro-d4 antikoerper, BAF45b antikoerper, NEUD4 antikoerper, Neud4 antikoerper, D4, zinc and double PHD fingers family 1 antikoerper, double PHD fingers 1 antikoerper, dpf1 antikoerper, DPF1 antikoerper, Dpf1 antikoerper

Hintergrund: DPF1 may have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Molekulargewicht: 42502

Gen-ID: 8193

NCBI Accession: NP_001128627, NP_001128628, NP_004638

UniProt: Q92782