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HLA-DMB Antikörper (AA 127-154)

HLA-DMB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB31771 unconjugated
Produktnummer ABIN1537808
  • Target Alle HLA-DMB Antikörper anzeigen
    HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
    Bindungsspezifität
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 127-154
    Reaktivität
    • 42
    • 1
    Human
    Wirt
    • 39
    • 3
    Kaninchen
    Klonalität
    • 38
    • 4
    Polyklonal
    Konjugat
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    Dieser HLA-DMB Antikörper ist unkonjugiert
    Applikation
    • 41
    • 31
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HLA-DMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human HLA-DMB.
    Klon
    RB31771
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product HLA-DMB Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    HLA-DMB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
    Andere Bezeichnung
    HLA-DMB (HLA-DMB Produkte)
    Synonyme
    RING7 antikoerper, D6S221E antikoerper, RT1.DMb antikoerper, RT1.Mb antikoerper, MHC-DMB antikoerper, major histocompatibility complex, class II, DM beta antikoerper, RT1 class II, locus DMb antikoerper, HLA-DMB antikoerper, RT1-DMb antikoerper, PATR-DMB antikoerper
    Hintergrund
    HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
    Molekulargewicht
    28943
    Gen-ID
    3109
    NCBI Accession
    NP_002109
    UniProt
    P28068
    Pathways
    Cancer Immune Checkpoints
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