SIN3A Antikörper (C-Term)

Produktnummer ABIN1536646

Produktdetails anti-SIN3A Antikörper

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Bindungsspezifität: AA 1078-1106, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: H

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.

Klon: RB40011

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Mouse Sin3a Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Andere Bezeichnung: Sin3a (SIN3A Produkte)

Synonyme: AW553200 antikoerper, Sin3 antikoerper, mKIAA4126 antikoerper, mSin3A antikoerper, zgc:162128 antikoerper, SIN3A antikoerper, SIN3 transcription regulator family member A antikoerper, transcriptional regulator, SIN3A (yeast) antikoerper, paired amphipathic helix protein Sin3a antikoerper, SIN3 transcription regulator family member Aa antikoerper, SIN3A antikoerper, Sin3a antikoerper, LOC100641919 antikoerper, sin3aa antikoerper, LOC100439524 antikoerper

Hintergrund: Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

Molekulargewicht: 145088

Gen-ID: 20466

NCBI Accession: NP_001103820, NP_001103821, NP_035508

UniProt: Q60520

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha