BAK1 Antikörper (AA 1-50)

Produktnummer ABIN1533215

Produktdetails anti-BAK1 Antikörper

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Bindungsspezifität: AA 1-50

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität:

Bak Antibody detects endogenous levels of total Bak protein.

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Bak.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Kommentare:

Unigene-Number: Hs.485139 (NCBI Gene Symbol: BAK1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-BAK1 Antikörper (ABIN1533215)

Plötz, Gillissen, Hossini, Daniel, Eberle: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." in: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).

Plötz, Hossini, Gillissen, Daniel, Stockfleth, Eberle: "Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK)." in: PLoS ONE, Vol. 7, Issue 4, pp. e34549, (2012) (PubMed).

Details zu BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Andere Bezeichnung: Bak (BAK1 Produkte)

Synonyme: BAK antikoerper, BAK-LIKE antikoerper, BCL2L7 antikoerper, CDN1 antikoerper, Bak antikoerper, N-BAK1 antikoerper, N-Bak antikoerper, Bak1 antikoerper, bak antikoerper, bak1 antikoerper, BCL2 antagonist/killer 1 antikoerper, BCL2-antagonist/killer 1 antikoerper, BCL2 antagonist/killer 1 L homeolog antikoerper, BAK1 antikoerper, Bak1 antikoerper, bak1.L antikoerper

Hintergrund:

Synonyms: Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like 7 protein, BAK1, BAK, BCL2L7

NCBI Gene Symbol: BAK1

Molekulargewicht: 23 kDa

Gen-ID: 578

OMIM: 600516

UniProt: Q16611, Q13014

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response